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KMID : 0382619890090020519
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Hanyang Journal of Medicine
1989 Volume.9 No. 2 p.519 ~ p.525
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Allergen Specific IgE and IgG Antibody Responses in Cat-induced Asthma Patients Undergoing Immunotherapy with Cat Extract
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Abstract
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Immunotherapy with a purified fraction of cat-hair and dander extract was relatively well tolerated in seven patients allergic to cat. Active treatment resulted in significant reductions in bronchial sensitivity (p<0.05) and skin test titer (p<0.01)
Furthermore, significant increases in IgG antibody to cat allergen 1 and decreases in IgE antibody to cat-1 in active treatment group comparing to placebo group (n = 9). In conclusion, cat extract immunotherapy would be useful, however, multicenter studies are required to confirm its validity.
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